What causes Chronic Kidney Disease?
The two main causes of chronic kidney disease are diabetes and high blood pressure. Glomerulonephritis is inflammation of the glomeruli, the small vessels in the nephron. If not treated, patients may suffer slow progressive damage to the kidneys and develop renal failure.Hypertension occurs with many cases of kidney diseases. Prolonged hypertension damages the small arteries in the kidneys. This may start a vicious cycle: damaged kidneys cause more serious hypertension which in turn brings more damage to the kidneys.
High blood sugar levels caused by diabetes damage blood vessels in the kidneys. If the blood sugar level remains high over many years, this damage gradually reduces the function of the kidneys. While uncontrolled high blood pressure damages blood vessels, which can lead to damage in the kidneys. And blood pressure often rises with chronic kidney disease, so high blood pressure may further damage kidney function even when another medical condition initially caused the disease. Infection is the most common disorder of the kidneys and the urinary tract. Uncomplicated urinary tract infections are very easy to treat.Stones are solid residues in the urinary tract that may cause obstruction to the flow of urine which in turn may lead to infection of the kidneys and subsequent scarring.Abnormalities in the urinary tract that are congenital or inborn may consequently lead to poor function, obstruction or infection of the kidneys.Some drugs, herbal medicine, solvents and insecticides can also harm the kidneys.